New hope for kids with rare kidney diseases in 2-Year drug trial

NCT ID NCT05003986

Summary

This study is testing an oral medication called sparsentan in children aged 1 to 18 with specific rare kidney diseases. The main goal is to see if the drug is safe and can reduce harmful protein loss in urine over 108 weeks. Researchers will enroll about 67 children to monitor their kidney function and how their bodies process the medicine.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alder Hey Children's NHS Foundation Trust

    RECRUITING

    Liverpool, L12 2AP, United Kingdom

  • Atrium Health Levine Children's Hospital

    COMPLETED

    Charlotte, North Carolina, 28203, United States

  • Azienda Ospedale Università di Padova

    RECRUITING

    Padua, 35128, Italy

  • C.S. Mott Children's Hospital

    RECRUITING

    Ann Arbor, Michigan, 48109-5008, United States

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Mercy Hospitals and Clinics

    RECRUITING

    Kansas City, Missouri, 64108, United States

  • Cohen Children's Medical Center

    RECRUITING

    New Hyde Park, New York, 11042, United States

  • Drottning Silvias Barn- och Ungdomssjukhus

    RECRUITING

    Gothenburg, 416 85, Sweden

  • Duke Molecular Physiology Institute

    RECRUITING

    Durham, North Carolina, 22710, United States

  • Emma Kinderziekenhuis

    RECRUITING

    Amsterdam, 1105 AZ, Netherlands

  • Fink Children's Ambulatory Care Center

    WITHDRAWN

    New York, New York, 10016, United States

  • Floating Hospital for Children at Tufts Medical Center

    WITHDRAWN

    Boston, Massachusetts, 02111, United States

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, 20122, Italy

  • Great Ormond Street Hospital for Children NHS Foundation Trust

    RECRUITING

    London, WC1N3JH, United Kingdom

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Hospital Universitari Vall d'Hebrón

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario La Paz

    RECRUITING

    Madrid, 28046, Spain

  • Hospital Universitario Virgen del Rocío

    RECRUITING

    Seville, 41013, Spain

  • IRCCS Istituto Giannina Gaslini

    RECRUITING

    Genova, 16147, Italy

  • Instytut Centrum Zdrowia Matki Polki

    WITHDRAWN

    Lodz, 93-338, Poland

  • Instytut Pomnik - Centrum Zdrowia Dziecka

    WITHDRAWN

    Warsaw, 04-730, Poland

  • Jersey Shore University Medical Center

    RECRUITING

    Neptune City, New Jersey, 07753, United States

  • Karolinska Universitetssjukhuset Huddinge

    RECRUITING

    Stockholm, 141 86, Sweden

  • Manchester University NHS Foundation Trust

    RECRUITING

    Manchester, M13 9WL, United Kingdom

  • NHS Greater Glasgow and Clyde, Royal Hospital for Children

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

  • Nemours Children's Hospital

    RECRUITING

    Wilmington, Delaware, 19803, United States

  • Nicklaus Children's Hospital

    RECRUITING

    Miami, Florida, 33155, United States

  • Ospedale Pediatrico Bambino Gesù

    RECRUITING

    Roma, 00165, Italy

  • Policlinico Bari Ospedale Pediatrico Giovanni XXIII

    RECRUITING

    Bari, 70126, Italy

  • Radboud Universitair Medisch Centrum

    RECRUITING

    Nijmegen, 6525 GA, Netherlands

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

  • St. Christopher's Hospital for Children

    WITHDRAWN

    Philadelphia, Pennsylvania, 19134, United States

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • UT Health - John P. and Kathrine G. McGovern Medical School

    WITHDRAWN

    Houston, Texas, 77030, United States

  • Uniklinik Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin

    RECRUITING

    Cologne, 50937, Germany

  • University Hospitals Bristol and Weston NHS Foundation Trust, Bristol Royal Hospital for Children

    RECRUITING

    Bristol, BS2 8BJ, United Kingdom

  • University of Iowa, Stead Family Children's Hospital

    WITHDRAWN

    Iowa City, Iowa, 52242, United States

  • University of Miami, Leonard M. Miller School of Medicine

    RECRUITING

    Miami, Florida, 33136, United States

  • University of Minnesota, Masonic Children's Hospital

    RECRUITING

    Minneapolis, Minnesota, 55454, United States

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Oklahoma Health Sciences Center (OUHSC)

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Universitätsklinikum Hamburg-Eppendorf

    RECRUITING

    Hamburg, 20246, Germany

  • Universitätsklinikum Heidelberg - Angelika Lautenschläger - Kinderklinik

    RECRUITING

    Heidelberg, 69120, Germany

  • Uniwersytecki Szpital Dziecięcy w Krakowie

    RECRUITING

    Krakow, 30-663, Poland

Conditions

Explore the condition pages connected to this study.