Targeted radiation bullet teams up with immune drug to fight tough kidney cancers

NCT ID NCT05239533

Summary

This study is testing whether combining a targeted radiation drug (177Lu-girentuximab) with an immunotherapy drug (nivolumab) is safe and effective for treating advanced kidney cancer that has a specific protein (CAIX). It is for adults with clear cell kidney cancer that has spread and who have already tried at least one prior treatment, including an immunotherapy drug. The main goals are to find the safest dose of the radiation drug and to see how well the combination shrinks tumors.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activites)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activites)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.