New cocktail of drugs shows promise for tough kidney cancer
NCT ID NCT05805501
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining newer immunotherapy drugs with a standard targeted therapy (axitinib) can safely control advanced kidney cancer. About 199 adults with untreated, advanced clear-cell renal cell carcinoma will receive one of three drug combinations. The main goal is to check for side effects and see how well the treatments work.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Asan Medical Center
Seoul, 05505, South Korea
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Barts & London School of Med
London, EC1A 7BE, United Kingdom
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Beijing Cancer Hospital
Beijing, 100142, China
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CHU Besançon - Hôpital Jean Minjoz
Besançon, 25030, France
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CHU de Bordeaux - Groupe Hospitalier Saint-André - Hopital Saint-Andre
Bordeaux, 33075, France
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Centre Francois Baclesse
Caen, 14076, France
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Centre Leon Berard
Lyon, 69373, France
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Centrum Onkologii im. Prof. Franciszka ?ukaszczyka
Bydgoszcz, 85-796, Poland
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Chonnam National University Hwasun Hospital
Jeollanam-do, 58128, South Korea
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Christie Hospital Nhs Trust
Manchester, M2O 4BX, United Kingdom
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Emory University
Atlanta, Georgia, 30322, United States
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitari i Politecnic La Fe
Valencia, 46026, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario Clínico San Carlos
Madrid, 28040, Spain
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Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
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Hospital Universitario Reina Sofia
Córdoba, Cordoba, 14004, Spain
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Hospital Universitario Virgen del Rocio
Seville, 41013, Spain
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Hospital de la Santa Creu i Sant Pau
Barcelona, 08025, Spain
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Institut Gustave Roussy
Villejuif, 94800, France
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Institut Sainte Catherine
Avignon, 84918, France
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Klinikum rechts der Isar der TU München
München, 81675, Germany
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Medizinische Hochschule Hannover
Hanover, 30625, Germany
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Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School
Nanjing, 210008, China
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National Cancer Center
Goyang-si, 10408, South Korea
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Peking University First Hospital
Beijing, 100034, China
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SCRI Oncology Partners
Nashville, Tennessee, 37203, United States
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Samsung Medical Center
Seoul, 06351, South Korea
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Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
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Sibley Memorial Hospital
Washington D.C., District of Columbia, 20016, United States
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, 21287, United States
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Studienpraxis Urologie
Nürtingen, 72622, Germany
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Sunshine Coast University Hospital
Birtinya, Queensland, 4575, Australia
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Szpital Kliniczny im. Heliodora ?wi?cickiego UM w Poznaniu
Późna, 60-569, Poland
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Szpital Specjalistyczny Podkarpacki O?rodek Onkologiczny
Brzozów, 36-200, Poland
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Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii
Krakow, 31-501, Poland
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Tianjin Cancer Hospital
Tianjin, 300060, China
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UC Irvine Medical Center
Orange, California, 92868, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390-9179, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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Universitätsklinikum "Carl Gustav Carus"
Dresden, 01307, Germany
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Universitätsklinikum Hamburg-Eppendorf Onkologisches Zentrum Medizinische Klinik II
Hamburg, 20246, Germany
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Universitätsklinikum Ulm
Ulm, 89081, Germany
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States