New hope for kidney cancer patients whose disease returns after initial therapy

NCT ID NCT07049926

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 36 times

Summary

This study is for people with a type of kidney cancer (clear cell renal cell carcinoma) that has come back during or within 2 years after finishing a certain kind of immunotherapy (anti-PD-[L]1). The goal is to test if combining different experimental drugs is safe and can shrink tumors. About 140 participants will receive these combinations, and researchers will monitor side effects and how well the cancer responds.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center ( Site 5800)

    RECRUITING

    Seoul, 05505, South Korea

    Contact Phone: •••-•••-••••

  • Bradfordhill ( Site 6101)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

    Contact Phone: •••-•••-••••

  • C.H.U. de Strasbourg Hopital de Hautepierre ( Site 5203)

    RECRUITING

    Strasbourg, Bas-Rhin, 67098, France

    Contact Phone: •••-•••-••••

  • Centre Eugene Marquis ( Site 5205)

    RECRUITING

    Rennes, Ille-et-Vilaine, 35042, France

    Contact Phone: •••-•••-••••

  • Centro de Estudios Clínicos SAGA ( Site 6110)

    RECRUITING

    Santiago, Region M. de Santiago, 7500653, Chile

    Contact Phone: •••-•••-••••

  • Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 6201)

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland

    Contact Phone: •••-•••-••••

  • Duke Cancer Institute ( Site 5015)

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-••••

  • Gustave Roussy ( Site 5202)

    RECRUITING

    Villejuif, Île-de-France Region, 94805, France

    Contact Phone: •••-•••-••••

  • Hospital Universitari Vall d'Hebron ( Site 5300)

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario Ramon y Cajal ( Site 5301)

    RECRUITING

    Madrid, Madrid, Comunidad de, 28034, Spain

    Contact Phone: •••-•••-••••

  • Institut Claudius Regaud ( Site 5200)

    RECRUITING

    Toulouse, Haute-Garonne, 31059, France

    Contact Phone: •••-•••-••••

  • Institut De Cancerologie De Lorraine ( Site 5204)

    RECRUITING

    Vandœuvre-lès-Nancy, Meurthe-et-Moselle, 54513, France

    Contact Phone: •••-•••-••••

  • Laura and Isaac Perlmutter Cancer Center ( Site 5016)

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center ( Site 5002)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 5026)

    RECRUITING

    Mineola, New York, 11501, United States

    Contact Phone: •••-•••-••••

  • Rabin Medical Center ( Site 5502)

    RECRUITING

    Petah Tikva, 4941492, Israel

    Contact Phone: •••-•••-••••

  • Rambam Health Care Campus ( Site 5500)

    RECRUITING

    Haifa, 3109601, Israel

    Contact Phone: •••-•••-••••

  • Samsung Medical Center ( Site 5801)

    RECRUITING

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-••••

  • Severance Hospital ( Site 5802)

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-••••

  • Sheba Medical Center ( Site 5501)

    RECRUITING

    Ramat Gan, 5265601, Israel

    Contact Phone: •••-•••-••••

  • Sourasky Medical Center ( Site 5503)

    RECRUITING

    Tel Aviv, 6423906, Israel

    Contact Phone: •••-•••-••••

  • St Bartholomew's Hospital ( Site 5401)

    RECRUITING

    London, London, City of, EC1A7BE, United Kingdom

    Contact Phone: •••-•••-••••

  • The Christie NHS Foundation Trust ( Site 5400)

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact Phone: •••-•••-••••

  • UCSF Medical Center at Mission Bay ( Site 5008)

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-••••

  • UPMC Cancer Center/Hillman Cancer Center ( Site 5017)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-••••

  • Uniwersyteckie Centrum Kliniczne ( Site 6202)

    RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-214, Poland

    Contact Phone: •••-•••-••••

  • Vanderbilt University Medical Center ( Site 5004)

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-••••

  • Western General Hospital ( Site 5402)

    RECRUITING

    Edinburgh, Edinburgh, City of, EH42XU, United Kingdom

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.