Can an experimental pill lift the fog of severe depression? a new trial puts KH607 to the test.

NCT ID NCT07101120

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This phase 2 trial is evaluating whether an experimental drug called KH607 can safely reduce symptoms of depression in adults with moderate or severe major depressive disorder. The study has two parts: first, all participants receive KH607 openly to check safety and how the drug moves through the body; then, some participants continue on KH607 while others receive a placebo, without knowing which they are taking. The main goal is to see if KH607 leads to a greater drop in depression scores compared to placebo over three weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called KH607, taken as a tablet
What this could lead to
If successful, KH607 could offer a new treatment option for people with moderate to severe depression who do not respond well to current therapies.
What could go wrong
This is an early phase 2 trial with a small number of participants, so results may not apply to everyone. The drug may cause side effects or prove no better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BeiJing AnDing Hospital capital medical University

    Beijing, China

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