Can a common painkiller curb opiate use in the ICU?
NCT ID NCT06819956
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a low dose of ketorolac, an NSAID, can safely reduce pain and the need for opiates in critically ill ICU patients. Thirty adults with pain will receive either ketorolac or a placebo for up to three days. The main goal is to see if this approach is feasible for a larger future trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketorolac (an NSAID painkiller)
What this could lead to
If it works, this could point toward a way to reduce opiate use in the ICU, lowering the risk of addiction after discharge.
What could go wrong
This is a small pilot study with only 30 patients, so results may not be definitive. NSAIDs carry risks of bleeding and kidney injury, though patients are closely monitored.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Alberta Hospital
RECRUITINGEdmonton, Alberta, T6G 2B7, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••