Could a ketone drink help stabilize bipolar disorder?
NCT ID NCT06335875
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small pilot study tested whether a ketone ester drink combined with a low-glycemic diet could help people with bipolar disorder. Fifteen adults with bipolar I or II took the supplement twice daily and made simple diet changes for several weeks. Researchers measured blood ketone levels and glucose stability to see if the approach was feasible and had any effect on mood symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketone ester beverage (Juvenescence Cognitive Switch™) and a low-glycemic-index diet
What this could lead to
If it works, this could point toward a dietary approach to help stabilize mood in bipolar disorder.
What could go wrong
This is a very small, early pilot study with only 15 people and no placebo group, so results may not be reliable or apply to everyone. The diet and supplement may be hard to stick with long-term.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Domino's Farms
Ann Arbor, Michigan, 48105, United States
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University Hospital
Ann Arbor, Michigan, 48109, United States