New hope for depression that Won't quit: ketamine meets talk therapy

This small pilot study tested whether giving intravenous ketamine alongside a specialized form of talk therapy (RO DBT) is safe and feasible for adults with moderate to severe depression that hasn't improved with standard treatments. The research aimed to see if this combined approach could help people achieve remission from depression and explored how it might work by measuring brain activity and feelings of social connection. The study involved 16 participants and was an early-phase trial focused on gathering initial data.