Ketamine: a speedier fix for severe depression?

NCT ID NCT06508710

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests whether a single dose of ketamine, given alongside the antidepressant venlafaxine, can relieve severe depression faster than venlafaxine alone. About 60 hospitalized adults with major depression will receive either ketamine or a placebo. The goal is to see if ketamine can reduce symptoms within days, potentially shortening hospital stays and lowering suicide risk.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bicetre Hospital - CRC

    NOT_YET_RECRUITING

    Le Kremlin-Bicêtre, 94250, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CEA/SHFJ

    ACTIVE_NOT_RECRUITING

    Orsay, 94401, France

  • EPS Barthélémy Durand

    NOT_YET_RECRUITING

    Étampes, 91152, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Psychiatry unit

    RECRUITING

    Le Kremlin-Bicêtre, France, 94270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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