Ketamine infusion may ease chronic nerve pain in brachial plexus injuries

NCT ID NCT04933149

ENROLLING_BY_INVITATION Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving ketamine during and after surgery can reduce chronic nerve pain in people with traumatic brachial plexus injuries. About 100 adults will receive a ketamine infusion during their reconstructive surgery and for 24 hours afterward. Researchers will measure changes in pain scores and opioid use over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ketamine
What this could lead to: If it works, this could point toward a new way to manage severe nerve pain after brachial plexus injuries, potentially reducing reliance on opioids.
What could go wrong: This is a small, early-phase study (100 people) at a single center, so results may not apply to everyone. Ketamine can cause side effects like dizziness or hallucinations, and the pain relief may be temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brachial plexus neuropathy brachial plexus neuropathy from injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRACHIAL PLEXUS INJURY

Contacts and locations

Locations

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

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