Could a single ketamine infusion ease daily headaches for months?
NCT ID NCT05306899
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a one-time high-dose intravenous ketamine infusion can reduce the number and intensity of headaches in people with chronic daily headaches. About 56 adults will receive either ketamine or a placebo (saline) and be followed for three months. The goal is to see if ketamine can safely provide lasting relief from this debilitating condition.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Toronto Western Hospital
RECRUITINGToronto, Ontario, M5T 2S8, Canada
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Women's College Hospital
RECRUITINGToronto, Ontario, M5S 1B2, Canada
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