Experimental cancer drug KD033 tested in early trial – but study halted

NCT ID NCT04242147

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase study tested an experimental drug called KD033 (SAR445710) in 45 adults with advanced or metastatic solid tumors. The main goal was to check safety and find the right dose, while also looking for any anti-cancer effects. The trial was terminated, so final results may be limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KD033 (SAR445710)

What this could lead to

If it works, this could point toward a new treatment option for advanced solid tumors.

What could go wrong

This is a very early Phase 1 trial, so safety and effectiveness are not yet proven. The study was terminated, meaning results may be limited or inconclusive.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fox Chase Cancer Center - 333 Cottman Avenue - Site 141

    Philadelphia, Pennsylvania, 19111, United States

  • Moffitt Cancer Center - Site 102

    Tampa, Florida, 33612, United States

  • Roswell Park Cancer Institute - 665 Elm St - Site 062

    Buffalo, New York, 14263, United States

  • UCLA Hematology/Oncology, 2020 Santa Monica Boulevard, Suite 600 - Site 042

    Santa Monica, California, 90404, United States

  • University of Pittsburgh Medical Center - Hillman Cancer Center - 5150 Centre Avenue, Suite 301 - Site 132

    Pittsburgh, Pennsylvania, 15232, United States