Breathing new hope: inhaled gene therapy trial for cystic fibrosis begins
NCT ID NCT05504837
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a new gene therapy called KB407, given as a mist through inhalation, in 20 adults with cystic fibrosis. The goal is to see if it is safe and can improve lung function by delivering a working copy of the CF gene to lung cells. Participants will receive increasing doses to find the best balance of safety and effect.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atrium Health Wake Forest Baptist Medical Center
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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New York Medical College/ Boston Children's Health Physicians
RECRUITINGHawthorne, New York, 10532, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Northwell Health Physicians
RECRUITINGNew York, New York, 10028, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Lukes CF Center of Idaho
RECRUITINGBoise, Idaho, 83712, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The Cystic Fibrosis Institute
RECRUITINGNorthfield, Illinois, 60093, United States
Contact Email: •••••@•••••
Contact
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University of Florida, Gainesville
RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact