Hope for autism irritability: new drug trial for kids

NCT ID NCT07284745

First seen Jan 04, 2026 · Last updated May 11, 2026 · Updated 18 times

Summary

This study tests a new medicine (KarXT + KarX-EC) to see if it can reduce irritability in children and teens with autism. About 176 participants aged 5 to 17 will receive either the drug or a placebo. The main goal is to check if the drug improves behavior and is safe to use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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Locations

  • Local Institution - 0007

    Brisbane, Queensland, 4101, Australia

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  • Local Institution - 0010

    Westmead, New South Wales, 2145, Australia

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  • Local Institution - 0031

    Anaheim, California, 92805, United States

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  • Local Institution - 0036

    Dothan, Alabama, 36303, United States

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  • Local Institution - 0041

    Dallas, Texas, 75243, United States

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  • Local Institution - 0045

    Melbourne, Victoria, 3052, Australia

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  • Local Institution - 0046

    La Plata, Buenos Aires, 1900, Argentina

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  • Local Institution - 0047

    Córdoba, X5003DCE, Argentina

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  • Local Institution - 0048

    Buenos Aires, Buenos Aires F.D., 1133, Argentina

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  • Local Institution - 0049

    Mendoza, 5502, Argentina

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  • Local Institution - 0056

    Kozhikode, Kerala, 673009, India

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  • Local Institution - 0061

    Nagpur, Maharashtra, 441108, India

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  • Local Institution - 0074

    Bountiful, Utah, 84010, United States

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  • Local Institution - 0092

    Chino, California, 91710, United States

  • Local Institution - 0099

    Gainesville, Florida, 32607, United States

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  • Local Institution - 0105

    Pittsburgh, Pennsylvania, 15213, United States

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  • Local Institution - 0110

    Las Vegas, Nevada, 89128, United States

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  • Local Institution - 0134

    Hamilton, Ontario, L8L 2X2, Canada

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  • Local Institution - 0135

    Kingston, Ontario, K7L4X3, Canada

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  • Local Institution - 0136

    Edmonton, Alberta, T6G 1Z1, Canada

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  • Local Institution - 0140

    Santiago del Estero, G4200DND, Argentina

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  • Local Institution - 0155

    Peachtree Corners, Georgia, 30071, United States

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  • Local Institution - 0160

    Bloomfield Hills, Michigan, 48302, United States

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  • Local Institution - 0181

    San Rafael, California, 94903, United States

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  • Local Institution - 0185

    Spring, Texas, 77381, United States

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  • Local Institution - 0187

    Montreal, Quebec, H3T 1C5, Canada

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  • Local Institution - 0205

    Toronto, Ontario, M4G 1R8, Canada

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  • Local Institution - 0218

    Kolkata, West Bengal, 700020, India

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  • Local Institution - 0220

    Detroit, Michigan, 48203, United States

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  • Local Institution - 0236

    Phoenix, Arizona, 85006, United States

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  • Local Institution - 0246

    Staten Island, New York, 10312, United States

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  • Local Institution - 0247

    West Chester, Ohio, 45069, United States

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  • Local Institution - 0252

    Colorado Springs, Colorado, 80910, United States

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  • Local Institution - 0256

    Hartford, Connecticut, 06106, United States

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  • Local Institution - 0257

    Glendale, California, 91203, United States

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  • Local Institution - 0260

    Richmond, Virginia, 23298-0341, United States

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  • Local Institution - 0263

    The Bronx, New York, 10461, United States

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  • Local Institution - 0264

    Boca Raton, Florida, 33428, United States

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  • Local Institution - 0266

    Chicago, Illinois, 60622, United States

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  • Local Institution - 0269

    Danville, Pennsylvania, 17821, United States

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  • Local Institution - 0271

    Provo, Utah, 84604, United States

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  • Local Institution - 0273

    Fort Worth, Texas, 76104, United States

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  • Local Institution - 0278

    Gainesville, Florida, 32607, United States

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  • Local Institution - 0286

    Melbourne, Victoria, 3168, Australia

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  • Local Institution - 0288

    Córdoba, X5004AOA, Argentina

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Conditions

Explore the condition pages connected to this study.