Can a simple gas ease cancer procedure pain?
NCT ID NCT00646945
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 37 times
Summary
This study tested a gas called Kalinox (a mix of nitrous oxide and oxygen) to see if it helps reduce pain during short invasive procedures in adult cancer patients. 204 participants were randomly assigned to receive either Kalinox or a placebo gas while undergoing procedures like spinal taps. The main goal was to measure pain levels using a standard pain scale.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centre Alexis Vautrin
Vandœuvre-lès-Nancy, 54 500, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Kalinox (50% nitrous oxide / 50% oxygen gas mixture)
What this could lead to
If it works, this could provide a safe, fast-acting pain relief option for cancer patients during short painful procedures like spinal taps.
What could go wrong
This is a completed phase 4 trial, so results are already known. The gas may cause side effects like nausea or dizziness, and it may not be more effective than standard pain relief or placebo.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.