New cancer drug enters first human trials for Tough-to-Treat tumors

NCT ID NCT05557045

Summary

This early-stage study is testing a new drug called JZP815 in people with advanced or metastatic solid tumors that have specific genetic changes in the MAPK pathway. The main goals are to find a safe dose, understand how the drug works in the body, and look for early signs that it might help shrink tumors. The study will enroll 332 adults who have run out of standard treatment options.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Florida Cancer Specialists - Lake Nona

    RECRUITING

    Orlando, Florida, 32827, United States

  • Florida Cancer Specialists - Sarasota

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • Oklahoma University

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • SCRI HealthOne

    RECRUITING

    Denver, Colorado, 80218, United States

  • Sidney Kimmel Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Tennessee Oncology - Nashville

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Texas Oncology- Central South

    RECRUITING

    Austin, Texas, 78731, United States

  • Texas Oncology- Gulf Coast

    RECRUITING

    The Woodlands, Texas, 77380, United States

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Virginica Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.