Late-Stroke hope: new drug could help hours after symptoms start

NCT ID NCT06990867

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called JX10 in people who have had a stroke and arrive at the hospital 4.5 to 24 hours later. The goal is to see if JX10 can improve recovery and reduce disability compared to a placebo. About 740 participants will be randomly assigned to receive JX10 or a placebo, and researchers will monitor their outcomes at 90 days, including bleeding risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
JX10 (a clot-dissolving drug)
What this could lead to
If it works, this could extend the treatment window for stroke patients, allowing more people to recover with minimal disability even if they arrive late at the hospital.
What could go wrong
This is still an early-to-mid-stage trial, so the drug may not prove effective or could cause dangerous bleeding in the brain. The results may not apply to all stroke types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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Locations

  • Corxel Investigational Site

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    Long Beach, California, 90806, United States

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    Sacramento, California, 95817, United States

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    Colorado Springs, Colorado, 80909, United States

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    Washington D.C., District of Columbia, 20007, United States

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    Delray Beach, Florida, 33484, United States

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    Chicago, Illinois, 60616, United States

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    Wichita, Kansas, 67214, United States

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    Baltimore, Maryland, 21215, United States

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    Kalamazoo, Michigan, 49048, United States

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    Traverse City, Michigan, 49684, United States

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    St Louis, Missouri, 63110, United States

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    Great Neck, New York, 11021, United States

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    New York, New York, 10029, United States

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    Toledo, Ohio, 43606, United States

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    Tulsa, Oklahoma, 74104, United States

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    Dallas, Texas, 75246, United States

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    Houston, Texas, 77030, United States

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    Ghent, 9000, Belgium

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    Blagoevgrad, Bulgaria

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    Burgas, Bulgaria

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    Pleven, Bulgaria

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    Plovdiv, Bulgaria

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    Sofia, 1606, Bulgaria

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    Edmonton, Canada

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    Kingston, Canada

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    Baotou, China

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    Beijing, China

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    Beijing, China

    Contact

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    Changchun, China

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    Guangzhou, China

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    Harbin, China

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    Kaili, China

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    Linfen, China

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    Shanghai, China

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    Shenyang, China

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    Suzhou, China

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    Weifang, China

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    Xuzhou, China

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    Altenburg, Germany

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    Leipzig, Germany

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    Lübeck, Germany

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    Trier, Germany

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    Athens, Greece

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    Chaïdári, Greece

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    Pátrai, Greece

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    Thessaloniki, Greece

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    Pavia, Italy

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    Roma, Italy

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    Fukuoka, Japan

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    Hyōgo, Japan

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    Kamakura, Japan

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    Meguro City, Japan

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    Mitaka, Japan

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    Miyagi, Japan

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    Yamagata, Japan

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    Yamaguchi, Japan

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    Daugavpils, Latvia

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    Riga, Latvia

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    Kaunas, Lithuania

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    Vilnius, Lithuania

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    Kuching, Malaysia

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    Braga, Portugal

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    Loures, Portugal

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    Belgrade, Serbia

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    Kragujevac, Serbia

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    Niš, Serbia

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    Novi Sad, Serbia

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    Seoul, South Korea

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    A Coruña, Spain

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    Albacete, Spain

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    Barcelona, Spain

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    Girona, Spain

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    Madrid, Spain

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    Málaga, Spain

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    Seville, Spain

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    Valencia, Spain

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    Bangkok, Thailand

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    Khon Kaen, Thailand

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    Harbin, China

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    Lille, France

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    Paris, France

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    Ibaraki, Japan

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    Toyota, Japan

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