New drug JR8603 enters first human trial for Hard-to-Treat cancers
NCT ID NCT06783569
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage trial tests the safety and effectiveness of a new drug called JR8603 in people with advanced solid tumors, including stomach and colorectal cancers, who have not responded to standard treatments. Participants receive JR8603 by IV infusion three times per month. The study will look for side effects and measure whether tumors shrink.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- JR8603 (a drug given by IV infusion)
- What this could lead to
- If successful, this could lead to a new treatment option for people with advanced solid tumors who have not responded to standard therapies.
- What could go wrong
- This is a very early Phase 1 trial with only 94 participants, so it is not yet known if JR8603 is safe or effective. There may be side effects, and the drug may not shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Harbin Medical University Cancer Hospital
RECRUITINGHarbin, Heiljiang Province, 150040, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Liaoning Cancer Hospital
RECRUITINGShenyang, Liaoning, 110042, China
Contact
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