New pill for tough blood cancers enters first human tests
NCT ID NCT04609826
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 20 times
Summary
This early-stage study tested a new drug called JNJ-74856665 in 153 people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). The main goal was to find safe doses and check for side effects. The drug works by blocking a protein that cancer cells need to grow. This is a first step to see if the drug is safe enough for larger studies.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Asan Medical Center
Seoul, 05505, South Korea
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CHRU Tours Hopital Bretonneau
Tours, 37000, France
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CHU de Nice Hopital de l Archet
Nice, 06200, France
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Centre Hospitalier Universitaire (CHU) de Bordeaux Hopital HautLeveque Centre Francois Magendie
Pessac, 33600, France
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Clinica Univ. de Navarra
Pamplona, 31008, Spain
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Hopital Saint Louis
Paris, 75010, France
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Hosp Clinic de Barcelona
Barcelona, 08036, Spain
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Hosp Univ Fund Jimenez Diaz
Madrid, 28040, Spain
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Hosp Univ Vall D Hebron
Barcelona, 08035, Spain
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Hosp. Univ. Marques de Valdecilla
Santander, 39008, Spain
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Inst. Cat. Doncologia-H Duran I Reynals
Barcelona, 08908, Spain
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Institut Universitaire du Cancer Toulouse Oncopole
Toulouse, 31059, France
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Kings College Hospital
London, SE5 9RF, United Kingdom
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Leicester Royal Infirmary
Leicester, LE1 5WW, United Kingdom
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Samsung Medical Center
Seoul, 06351, South Korea
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Seoul National University Hospital
Seoul, 3080, South Korea
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Severance Hospital Yonsei University Health System
Seoul, 03722, South Korea
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The Catholic University of Korea Seoul St Marys Hospital
Seoul, 06591, South Korea
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The Christie Nhs Foundation Trust
Manchester, M20 4BX, United Kingdom
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University College London Hospitals
London, NW1 2BU, United Kingdom
Conditions
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