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Engineered immune cells take on Hard-to-Treat lymphoma

NCT ID NCT04245839

Ongoing Disease control Sponsor: Celgene Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tests a treatment called JCAR017, which uses a patient's own immune cells that are modified in a lab to better fight cancer. It is for adults with a type of slow-growing lymphoma (follicular or marginal zone) that has come back or not responded to prior treatments. The goal is to see how well the therapy shrinks tumors and to monitor side effects for up to 5 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Local Institution - 100

    Boston, Massachusetts, 02114, United States

  • Local Institution - 101

    Boston, Massachusetts, 02215, United States

  • Local Institution - 102

    Baltimore, Maryland, 21201, United States

  • Local Institution - 103

    Chicago, Illinois, 60611, United States

  • Local Institution - 104

    Houston, Texas, 77030, United States

  • Local Institution - 105

    New Haven, Connecticut, 06520, United States

  • Local Institution - 107

    Aurora, Colorado, 80045, United States

  • Local Institution - 108

    Seattle, Washington, 98109, United States

  • Local Institution - 109

    Niles, Illinois, 60714, United States

  • Local Institution - 110

    Charlotte, North Carolina, 28204, United States

  • Local Institution - 111

    Santa Monica, California, 90095, United States

  • Local Institution - 112

    Cleveland, Ohio, 44195, United States

  • Local Institution - 113

    Sioux Falls, South Dakota, 57105, United States

  • Local Institution - 114

    Portland, Oregon, 97213, United States

  • Local Institution - 115

    Charlottesville, Virginia, 22903, United States

  • Local Institution - 116

    New York, New York, 10021, United States

  • Local Institution - 117

    Philadelphia, Pennsylvania, 19104, United States

  • Local Institution - 119

    Houston, Texas, 77030, United States

  • Local Institution - 121

    Dallas, Texas, 75230-2510, United States

  • Local Institution - 122

    Iowa City, Iowa, 52242, United States

  • Local Institution - 123

    Morristown, New Jersey, 07960, United States

  • Local Institution - 124

    Wichita, Kansas, 67124, United States

  • Local Institution - 127

    Detroit, Michigan, 48201, United States

  • Local Institution - 150

    Toronto, Ontario, M5G 2M9, Canada

  • Local Institution - 151

    Montreal, Quebec, H1T 2M4, Canada

  • Local Institution - 200

    London, NW1 2PG, United Kingdom

  • Local Institution - 201

    Manchester, M20 4BX, United Kingdom

  • Local Institution - 250

    Pierre-Bénite, 69495, France

  • Local Institution - 251

    Montpellier, 34295, France

  • Local Institution - 252

    Lille, 59037, France

  • Local Institution - 253

    Rennes, 35023, France

  • Local Institution - 254

    Toulouse, 31100, France

  • Local Institution - 255

    Paris, 75475, France

  • Local Institution - 300

    Bergamo, 24127, Italy

  • Local Institution - 301

    Naples, 80131, Italy

  • Local Institution - 350

    Salamanca, 37007, Spain

  • Local Institution - 351

    Seville, 41013, Spain

  • Local Institution - 353

    Madrid, 28007, Spain

  • Local Institution - 450

    Vienna, 1090, Austria

  • Local Institution - 500

    Ulm, Baden-Wurttemberg, 89081, Germany

  • Local Institution - 501

    Cologne, 50937, Germany

  • Local Institution - 502

    Munich, 81377, Germany

  • Local Institution - 503

    Karlsruhe, 76135, Germany

  • Local Institution - 504

    Regensburg, Bavaria, 93053, Germany

  • Local Institution - 550

    Chuo-ku, Tokyo, 1040045, Japan

  • Local Institution - 551

    Minato-ku, Tokyo, 105-8470, Japan

  • Local Institution - 552

    Fukuoka, 812-8582, Japan

  • Local Institution - 553

    Sapporo, Hokkaido, 0608648, Japan

  • Local Institution - 600

    Stockholm, 14186, Sweden

Conditions

Explore the condition pages connected to this study.

LYMPHOMA NON-HODGKIN