New Immunotherapy-Chemo cocktail aims to boost cervical cancer survival

NCT ID NCT07244965

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding the immunotherapy drug ivonescimab to chemotherapy before standard chemoradiation can improve outcomes for women with high-risk, locally advanced cervical cancer. About 42 participants will receive two cycles of the combination, then proceed to standard chemoradiation. The study measures how long the cancer stays under control and how well the tumors shrink.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ivonescimab (an immunotherapy drug) combined with paclitaxel and cisplatin (chemotherapy)

What this could lead to

If it works, this could offer a new treatment approach to shrink tumors before standard chemoradiation, potentially improving survival for women with advanced cervical cancer.

What could go wrong

This is a small, early-phase trial with only 42 participants and no comparison group. The combination may cause significant side effects, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical cancer cervical carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Women's Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310000, China