Could a common numbing drug cut Post-Surgery opioid use?

NCT ID NCT07076641

Not yet recruiting Symptom relief Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests whether giving lidocaine through an IV, along with a spinal morphine injection, can lower the amount of morphine patients need after major digestive or abdominal surgery. About 76 adults having planned open abdominal surgery will be randomly assigned to receive either lidocaine or a placebo. The goal is to see if lidocaine helps control pain better and reduces morphine use in the first 48 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine (intravenous)
What this could lead to: If it works, this could offer a way to reduce morphine use after major abdominal surgery, potentially lowering side effects like nausea or drowsiness.
What could go wrong: This is a small, early-stage trial with only 76 participants, so results may not apply to everyone. Lidocaine can cause side effects like dizziness or heart issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Digestive System Diseases digestive system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIGESTIVE SYSTEM DISEASE SURGERY

Contacts and locations

Locations

Hôpital Privé Jean Mermoz

Lyon, 69008, France

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