New pill aims to revive fetal hemoglobin and calm sickle cell crisis
NCT ID NCT06546670
First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 23 times
Summary
This early-stage study tests a new drug, ITU512, in healthy volunteers and people with sickle cell disease. The goal is to see if it safely boosts fetal hemoglobin, a natural protein that can reduce painful sickle cell complications. The trial first checks safety and dosing in healthy adults, then moves to patients to measure effectiveness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Boston Childrens Hospital
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lifespan
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Quotient Sciences Sea View
COMPLETEDMiami, Florida, 33126, United States
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University of Alabama Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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