What Trade-Offs are ITP patients willing to make for better treatment?
NCT ID NCT07786077
First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time
Summary
This study asks people living with primary immune thrombocytopenia (ITP) in the United States to share their treatment preferences through a survey. Using a method called a discrete choice experiment, participants will weigh different treatment features, such as effectiveness, side effects, and convenience. The goal is to understand what trade-offs patients are willing to make between benefits and risks, and how personal characteristics like age, symptoms, and treatment history influence those choices. The findings could help shape future ITP treatments to better align with patient values.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors and drug developers design treatments that better match what patients with ITP truly value, improving satisfaction and adherence.
- What could go wrong
- This is a survey study, not a treatment trial, so it won't directly test any new therapy. Results depend on how well the participants' stated preferences reflect real-world decisions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults receiving 1L or 2L treatment for ITP who reside in the US.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: 1. Currently living in the US. 2. Aged 18 years and older on the day of providing informed consent. 3. A diagnosis of primary ITP: a. For participants receiving first-line (1L) treatment for ITP: i. Diagnosed with primary ITP and started 1L corticosteroids within 3 months of diagnosis ii. Responded to 1L corticosteroid treatment \[with or without intravenous immunoglobulin (IVIg)\] b. For participants receiving second-line (2L) treatment for ITP: i. Assessed as needing or are taking thrombopoietin receptor agonist (TPO-RA) treatment for 2L treatment ii. Has previously been treated with a 1L corticosteroid (with or without IVIg) with insufficient response or relapse Exclusion criteria: 1. For participants receiving 1L treatment for ITP only: Previous or current use of treatments different from corticosteroids and/or IVIg/anti-D immunoglobulin. 2. For participants receiving 2L ITP treatment: Previous or current use of treatments different from corticosteroids, IVIg/anti-D immunoglobulin or one TPO-RA (i.e. patients who have used any treatment in a third-line setting are ineligible).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Novartis
RECRUITINGEast Hanover, New Jersey, 07936, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New combo therapy aims to boost platelets in immune disorder
- Can a vitamin a drug boost platelets in Hard-to-Treat ITP?
- Real-World study to track Eltrombopag's effectiveness in ITP patients
- New combo aims to boost platelets in stubborn ITP