Real-World study to track Eltrombopag's effectiveness in ITP patients
NCT ID NCT07587723
First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This study looks at how eltrombopag is actually used and how well it works in patients with immune thrombocytopenia (ITP) who have already tried steroids. Researchers will collect data from healthcare providers in the US, UK, and Germany, focusing on platelet count improvements within 12 weeks. The goal is to understand real-world treatment patterns and outcomes, not to test a new drug.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- eltrombopag
- What this could lead to
- If successful, this study could provide real-world evidence on how well eltrombopag works for immune thrombocytopenia outside of clinical trials.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be influenced by patient selection and other factors. It does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients diagnosed with primary ITP who were treated with eltrombopag following corticosteroid treatment.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: HCP inclusion criteria: 1. A licensed HCP (e.g., internal medicine specialist, hematologist, hematologist-oncologist or immunologist etc.) involved in the management of adult patients with primary ITP. 2. Actively involved in treatment decision-making for primary ITP patients at the time of the study. 3. Have a minimum of 3 years of experience managing patients with primary ITP. 4. Currently, managing an average of at least 2 adult primary ITP patients per month, including those treated with eltrombopag. 5. Able and willing to complete a web-based survey (approximately 60 to 70 minutes) and abstract data from 2 eligible patient charts. 6. Practicing in one of the study countries (US, UK, or Germany). 7. Have access to a computer or mobile device with internet connectivity to complete the survey. 8. Not listed as inactive or retired in the panel database. Patient-level inclusion criteria: 1. Confirmed diagnosis of primary ITP. 2. Aged ≥18 years at the time of diagnosis. 3. Received first-line corticosteroid therapy (with or without intravenous immune globulin \[IVIg\]). 4. Initiated eltrombopag treatment (with or without corticosteroids) as first non-steroidal ITP treatment between 01 January 2020 and 31 December 2024. 5. Have at least 6 months of follow-up data available after the index date (unless deceased within that period). Exclusion criteria: HCP exclusion criteria: 1. Currently employed by a pharmaceutical company or regulatory authority involved in the approval or marketing of treatments for primary ITP. 2. Unable to provide data for patients who meet the study's inclusion criteria. 3. Not currently managing patients with primary ITP or are not involved in treatment decisions for these patients. Patient-level exclusion criteria: 1\. Diagnosis of Evans syndrome, secondary ITP, or non-immune thrombocytopenia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Novartis
RECRUITINGBasel, CH-4056, Switzerland
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Other studies related to the condition(s) this trial covers.
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- Experimental injection aims to boost platelets in chronic blood disorder
- New combo therapy aims to boost platelets in immune disorder