Real-World study to track Eltrombopag's effectiveness in ITP patients

NCT ID NCT07587723

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study looks at how eltrombopag is actually used and how well it works in patients with immune thrombocytopenia (ITP) who have already tried steroids. Researchers will collect data from healthcare providers in the US, UK, and Germany, focusing on platelet count improvements within 12 weeks. The goal is to understand real-world treatment patterns and outcomes, not to test a new drug.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
eltrombopag
What this could lead to
If successful, this study could provide real-world evidence on how well eltrombopag works for immune thrombocytopenia outside of clinical trials.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by patient selection and other factors. It does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients diagnosed with primary ITP who were treated with eltrombopag following corticosteroid treatment.

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: HCP inclusion criteria: 1. A licensed HCP (e.g., internal medicine specialist, hematologist, hematologist-oncologist or immunologist etc.) involved in the management of adult patients with primary ITP. 2. Actively involved in treatment decision-making for primary ITP patients at the time of the study. 3. Have a minimum of 3 years of experience managing patients with primary ITP. 4. Currently, managing an average of at least 2 adult primary ITP patients per month, including those treated with eltrombopag. 5. Able and willing to complete a web-based survey (approximately 60 to 70 minutes) and abstract data from 2 eligible patient charts. 6. Practicing in one of the study countries (US, UK, or Germany). 7. Have access to a computer or mobile device with internet connectivity to complete the survey. 8. Not listed as inactive or retired in the panel database. Patient-level inclusion criteria: 1. Confirmed diagnosis of primary ITP. 2. Aged ≥18 years at the time of diagnosis. 3. Received first-line corticosteroid therapy (with or without intravenous immune globulin \[IVIg\]). 4. Initiated eltrombopag treatment (with or without corticosteroids) as first non-steroidal ITP treatment between 01 January 2020 and 31 December 2024. 5. Have at least 6 months of follow-up data available after the index date (unless deceased within that period). Exclusion criteria: HCP exclusion criteria: 1. Currently employed by a pharmaceutical company or regulatory authority involved in the approval or marketing of treatments for primary ITP. 2. Unable to provide data for patients who meet the study's inclusion criteria. 3. Not currently managing patients with primary ITP or are not involved in treatment decisions for these patients. Patient-level exclusion criteria: 1\. Diagnosis of Evans syndrome, secondary ITP, or non-immune thrombocytopenia.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Novartis

    RECRUITING

    Basel, CH-4056, Switzerland

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