Zapping the brain to save memories: early trial shows promise
NCT ID NCT05327257
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small pilot study tested whether a non-invasive brain stimulation technique called iTBS rTMS could improve memory in 25 adults with mild cognitive impairment (MCI). The main goal was to see if the treatment was feasible and acceptable, while also checking for any memory benefits. Results are still being analyzed, but this early work could lead to larger trials exploring a drug-free way to ease memory symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intermittent theta burst stimulation (iTBS) repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could point toward a non-drug treatment to ease memory problems in people with mild cognitive impairment.
What could go wrong
This is a very small, early pilot study with only 25 participants, focused on feasibility. It may not show clear memory benefits, and results may not apply to everyone with MCI.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States