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Could a brain zap help when PTSD talk therapy falls short?

NCT ID NCT07693088

Not yet recruiting Symptom relief Sponsor: Aarhus University Hospital Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether adding a type of brain stimulation called intermittent theta-burst stimulation (iTBS) can help adults with post-traumatic stress disorder (PTSD) who do not improve enough with standard eye movement desensitization and reprocessing (EMDR) therapy alone. Participants first receive weekly EMDR sessions. Those who still have significant symptoms after seven sessions then receive iTBS (targeted to a brain region involved in emotion regulation) for four weeks while continuing EMDR. The main goals are to see if this combined approach is feasible, safe, and tolerable, and to gather early data on symptom changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Intermittent theta-burst stimulation (iTBS) device
What this could lead to
If this approach is feasible and shows promise, it could point toward a way to help people with PTSD who do not get enough relief from standard therapy alone.
What could go wrong
This is a very small pilot study with only 15 people, so results may not apply widely. The added stimulation may not provide extra benefit and could cause side effects like discomfort or headache.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

combat disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PTSD - POST TRAUMATIC STRESS DISORDER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aarhus University Hospital

    Aarhus N, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Regional Psychiatry Central Jutland

    Viborg, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Regional Psychiatry Horsens

    Horsens, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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