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Massive global registry launches to track prostate cancer care worldwide
NCT ID NCT03151629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is a large international registry that will follow at least 5,000 men with advanced prostate cancer for five years or more. Researchers will collect detailed information on treatments, side effects, and quality of life to see which approaches work best. The goal is to improve care and identify markers that predict how well a treatment will work.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2017
- Expected to finish
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Jan 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Metastatic hormone sensitive prostate cancer (mHSPC): Prostate cancer patients diagnosed with histologically confirmed cancer with radiological evidence of metastatic disease and on ADT for no more than 90 days. Castration resistant prostate cancer (CRPC): Prostate cancer patients (with or without radiological evidence of metastatic disease) with a confirmed rising PSA (at least two measures) while on ADT or orchiectomy or castrate level of testosterone as determined by investigator. Prostate cancer patients with mixed histological types may participate in this Registry.
- Ages
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21 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
• Willing and able to provide written informed consent and privacy authorization for the release of personal health information. NOTE: Privacy authorization may be either included in the informed consent or obtained separately. * Males 21 years of age and above * Histological or cytological confirmed prostate adenocarcinoma from TRUS biopsy, radical prostatectomy or TURP Or Documented histopathology or cytopathology of prostate adenocarcinoma from a biopsy of a metastatic site Or Metastatic disease typical of prostate cancer (i.e., involving bone or pelvic lymph nodes or para-aortic lymph nodes) AND a serum concentration of PSA \>20ng/mL at the time of initial prostate cancer diagnosis * No previous diagnosis of a second, non-prostate malignancy that requires additional systemic therapy except cancer in situ of bladder and basal cell cancer of skin
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
75 sites in 10 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Australian Prostate Centre
RECRUITINGMelbourne N., Australia
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Australian Urology Associates
RECRUITINGMelbourne, Australia
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BC Cancer Agency
RECRUITINGVancouver, British Columbia, Canada
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Baptist Clinical Research Institute
RECRUITINGMemphis, Tennessee, 38120, United States
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Baylor College of Medicine
COMPLETEDHouston, Texas, 77030, United States
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Beacon Hospital
RECRUITINGDublin, Leinster, Ireland
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CHU de Québec-Université Laval
RECRUITINGQuébec, Quebec, Canada
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Centre hospitalier de l'Université de Montréal (CHUM)
RECRUITINGMontreal, Quebec, Canada
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Centro Paulista de Oncologia
COMPLETEDSão Paulo, Brazil
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Centro de Pesquisa em Oncologia
ACTIVE_NOT_RECRUITINGPorto Alegre, Brazil
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Chesapeake Urology Associates
TERMINATEDTowson, Maryland, 21204, United States
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Clatterbridge Cancer Centre
RECRUITINGMetropolitan Borough of Wirral, United Kingdom
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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Cross Cancer Institute (Alberta Health Services)
RECRUITINGEdmonton, Alberta, T6G 1Z2, Canada
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Delnor Cancer Center
RECRUITINGGeneva, Illinois, 60134, United States
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Doylestown Health
COMPLETEDDoylestown, Pennsylvania, 18901, United States
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Duke Cancer Network
RECRUITINGDurham, North Carolina, 27710, United States
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Durham VA Medical Center
RECRUITINGDurham, North Carolina, 27705, United States
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Eastern Health (Box Hill Hospital)
RECRUITINGBox Hill, Victoria, Australia
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Emory Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
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Ente Ospedaliero Cantonale
ACTIVE_NOT_RECRUITINGBellinzona, Bellinzona, 6500, Switzerland
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Epworth Healthcare
RECRUITINGMount Waverley, Victoria, 3149, Australia
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Federal Medical Centre Abeokuta
ACTIVE_NOT_RECRUITINGAbeokuta, Nigeria
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Fox Chase Cancer Center - Temple Health
RECRUITINGPhiladelphia, Pennsylvania, 19134, United States
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Fundació Institut Mar d'Investigacions Mèdiques (Hospital del Mar).
ACTIVE_NOT_RECRUITINGBarcelona, Spain
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Groote Schuur Hospital
ACTIVE_NOT_RECRUITINGCape Town, 7925, South Africa
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Guys St Thomas NHS Foundation Trust
RECRUITINGLondon, United Kingdom
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Hospital Beneficência Portuguesa
TERMINATEDBela Vista, São Paulo, Brazil
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Hospital Clinico San Carlos
ACTIVE_NOT_RECRUITINGMadrid, Spain
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Hospital Clínic de Barcelona
ACTIVE_NOT_RECRUITINGBarcelona, Barcelona, Spain
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Hospital Provincial de Castellón
ACTIVE_NOT_RECRUITINGCastellon, Spain
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Hospital Universitario 12 de Octubre
ACTIVE_NOT_RECRUITINGMadrid, Spain
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Hospital Universitario Central de Asturias
ACTIVE_NOT_RECRUITINGOviedo, 33011, Spain
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Hospital Universitario La Princesa
ACTIVE_NOT_RECRUITINGMadrid, 28006, Spain
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Hospital Universitario Miguel Servet (Zaragoza)
ACTIVE_NOT_RECRUITINGZaragoza, Spain
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Hospital Universitario Virgen de la Victoria
ACTIVE_NOT_RECRUITINGMálaga, Málaga, Spain
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Institut Catalá d'Oncologia Badalona
ACTIVE_NOT_RECRUITINGBadalona, Spain
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Instituto Câncer do Estado de São Paulo
COMPLETEDSão Paulo, Brazil
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Instituto Valenciano de Oncología
ACTIVE_NOT_RECRUITINGValencia, Valencia, 46009, Spain
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Instituto do Câncer e Transplante
COMPLETEDCuritiba, Brazil
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Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
RECRUITINGBaltimore, Maryland, 21231, United States
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Juravinski Cancer Centre
RECRUITINGHamilton, Ontario, Canada
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Kantonsspital Graubünden
ACTIVE_NOT_RECRUITINGChur, Switzerland
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Kantonsspital St. Gallen
ACTIVE_NOT_RECRUITINGSankt Gallen, Switzerland
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Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
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Kishwaukee Cancer Center
RECRUITINGDeKalb, Illinois, 60115, United States
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Lagos State University Teaching Hospital
ACTIVE_NOT_RECRUITINGLagos, Nigeria
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Lancashire Teaching Hospitals NHS Foundation Trust
RECRUITINGPreston, PR2 9HT, United Kingdom
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Lister Hospital
RECRUITINGStevenage, Hertfordshire, SG1 4AB, United Kingdom
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Macquarie University
RECRUITINGSydney, New South Wales, Australia
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Mayo Clinic Jacksonville
RECRUITINGJacksonville, Florida, 32224, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Memphis VA Medical Center
RECRUITINGMemphis, Tennessee, 38104, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Morehouse School of Medicine
RECRUITINGAtlanta, Georgia, 30310, United States
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Mount Vernon Cancer Centre
RECRUITINGNorthwood, Middlesex, HA6 2RN, United Kingdom
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NewYork-Presbyterian Brooklyn Methodist Hospital
RECRUITINGBrooklyn, New York, 11215, United States
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Onkozentrum Zürich
ACTIVE_NOT_RECRUITINGZurich, 8039, Switzerland
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Orebro University Hospital
RECRUITINGÖrebro, Sweden
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Oregon Health & Science University Hospital
RECRUITINGPortland, Oregon, 97239, United States
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Oslo University Hospital
RECRUITINGOslo, 0379, Norway
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Ottawa Hospital Cancer Centre
RECRUITINGOttawa, Ontario, Canada
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Peter MacCallum Cancer Centre
RECRUITINGMelbourne, Victoria, 3000, Australia
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Princess Alexandra Hospital
RECRUITINGWoolloongabba, Queensland, Australia
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Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, M5G 2C1, Canada
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Ralph H. Johnson VA Medical Center
RECRUITINGCharleston, South Carolina, 29401, United States
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Reading Health System
RECRUITINGWest Reading, Pennsylvania, 19611, United States
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Redland Hospital
RECRUITINGCleveland, Queensland, Australia
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Robert H. Lurie Comprehensive Cancer Center of Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Roswell Park Comprehensive Cancer Center
ACTIVE_NOT_RECRUITINGBuffalo, New York, 14203, United States
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Royal Brisbane & Women's Hospital
RECRUITINGHerston, Brisbane, Australia
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Sheffield Teaching Hospitals NHS Foundation Trust
RECRUITINGSheffield, S10 2SB, United Kingdom
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Skane University Hospital
RECRUITINGMalmö, Skåne County, Sweden
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Sligo University Hospital
RECRUITINGSligo, F91 H684, Ireland
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South Tyneside District Hospital
TERMINATEDSouth Shields, NE34 0PL, United Kingdom
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St. Vincent's Hospital Sydney
RECRUITINGDarlinghurst, New South Wales, Australia
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St. Vincent's University Hospital
RECRUITINGDublin, Ireland
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Steve Biko Academic Hospital
ACTIVE_NOT_RECRUITINGPretoria, Gauteng, 0084, South Africa
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Sunderland Royal Hospital
TERMINATEDSunderland, SR4 7TP, United Kingdom
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Tacchini Hospital
ACTIVE_NOT_RECRUITINGBento Gonçalves, Rio Grande do Sul, 95700-084, Brazil
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Tallaght University Hospital
RECRUITINGDublin, D24 NR0A, Ireland
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The Christie NHS Foundation Trust
RECRUITINGManchester, United Kingdom
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The Medical Oncology Centre of Rosebank
ACTIVE_NOT_RECRUITINGJohannesburg, Gauteng, 2196, South Africa
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The Royal Marsden NHS Foundation Trust
RECRUITINGLondon, United Kingdom
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The University of the West Indies - Cave Hill Campus
RECRUITINGBridgetown, Barbados
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The University of the West Indies - Mona Campus
RECRUITINGKingston, Jamaica
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Thomas Jefferson University
ACTIVE_NOT_RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Tulane University
ACTIVE_NOT_RECRUITINGNew Orleans, Louisiana, 70118, United States
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Umea University Hospital
RECRUITINGUmeå, Sweden, 907 37, Sweden
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University Hospital Southampton NHS Foundation Trust
RECRUITINGSouthampton, Hampshire, United Kingdom
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University Hospitals Cleveland Medical Center
RECRUITINGCleveland, Ohio, 44106, United States
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University Hospitals of Morecambe Bay NHS Foundation Trust
RECRUITINGLancaster, United Kingdom
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University of Alabama- Tuscaloosa
RECRUITINGTuscaloosa, Alabama, 35487, United States
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University of Alabama-Birmingham
COMPLETEDBirmingham, Alabama, 35233, United States
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University of California - Los Angeles
TERMINATEDLos Angeles, California, 90024, United States
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University of California San Diego
RECRUITINGSan Diego, California, 92037, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Florida
TERMINATEDGainesville, Florida, 32611, United States
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University of Illinois at Chicago
RECRUITINGChicago, Illinois, 60607, United States
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University of Ilorin Teaching Hospital
ACTIVE_NOT_RECRUITINGIlorin, Nigeria
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University of Maiduguri Teaching Hospital
ACTIVE_NOT_RECRUITINGMaiduguri, Nigeria
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University of Massachusetts Memorial Medical Center
RECRUITINGWorcester, Massachusetts, 01655, United States
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University of Michigan
TERMINATEDAnn Arbor, Michigan, 48109, United States
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University of Mississippi Medical Center
RECRUITINGJackson, Mississippi, 39216, United States
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University of Nairobi
RECRUITINGNairobi, Kenya
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States
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University of Washington Medical Center
ACTIVE_NOT_RECRUITINGSeattle, Washington, 98195, United States
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University of Wisconsin Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53705, United States
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Universitätsspital Basel
ACTIVE_NOT_RECRUITINGBasel, Switzerland
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Universitätsspital Zürich
ACTIVE_NOT_RECRUITINGZurich, Switzerland
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VA Western New York Healthcare System
TERMINATEDBuffalo, New York, 14215, United States
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Vall d'Hebron Institute of Oncology
ACTIVE_NOT_RECRUITINGBarcelona, Catalonia, Spain
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Velindre Cancer Centre
RECRUITINGCardiff, United Kingdom
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Warrenville Cancer Center
RECRUITINGWarrenville, Illinois, 60555, United States
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Weill Cornell Medical Center
RECRUITINGNew York, New York, 10065, United States
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Westmead Hospital
RECRUITINGSydney, New South Wales, Australia
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William Jennings Bryan Dorn VAMC
TERMINATEDColumbia, South Carolina, 29209, United States
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Yale University
RECRUITINGNew Haven, Connecticut, 06502, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Radioactive missile aims at prostate cancer that spread
- New PET tracer targets ACP3 to spot prostate cancer
- Can a One-Week radiation course match four weeks for prostate cancer?
- Can a new PET tracer spot hidden prostate cancer spread?
- Can a gel cushion shield the rectum during prostate radiation?
- A scanner in the operating room could show surgeons exactly where prostate cancer remains