Electric pulses zapping liver tumors: new hope for colorectal cancer patients?
NCT ID NCT07191548
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a procedure called irreversible electroporation (IRE), also known as Nanoknife, to treat liver tumors that have spread from colorectal cancer. IRE uses short electrical pulses to destroy cancer cells while sparing nearby blood vessels and bile ducts. The trial will enroll 50 adults who have already had chemotherapy and will measure how many tumors are completely gone after 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Irreversible electroporation (Nanoknife) - a procedure using electrical pulses to destroy cancer cells
- What this could lead to
- If successful, this could offer a new, targeted way to treat liver metastases from colorectal cancer without damaging nearby healthy tissue.
- What could go wrong
- This is an early-stage study with only 50 participants, so results may not apply to everyone. The procedure carries risks like bleeding or infection, and it may not fully eradicate all tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Manchester Royal Infirmiary
Manchester, M13 9WL, United Kingdom
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