Zapping liver cancer: electric pulses target tumors, spare healthy tissue

NCT ID NCT07192731

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called irreversible electroporation (IRE), which uses short electrical pulses to kill liver cancer cells while leaving nearby healthy tissue unharmed. It is for people with early-stage liver cancer (HCC) who have good liver function. The goal is to see if IRE can completely destroy tumors after 6 months, offering a less invasive alternative to surgery or heat-based ablation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Irreversible electroporation (IRE) device (Nanoknife)

What this could lead to

If successful, this could offer a targeted, non-surgical option to destroy liver tumors while sparing healthy tissue, potentially controlling liver cancer without major side effects.

What could go wrong

This is an early-stage, small study (50 people) with no comparison group, so results may not apply widely. The procedure carries risks like bleeding or infection, and it may not fully eradicate tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Manchester Royal Infirmiary

    Manchester, M13 9WL, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••