New pill aims to tame lupus kidney damage

NCT ID NCT06717815

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new daily pill, IPG11406, in 36 adults with lupus nephritis—a kidney complication of lupus. The study checks if the drug is safe and whether it can reduce protein in the urine and improve kidney function. It is too soon to know if it works, but the goal is to better control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IPG11406 (a tablet that blocks a protein called GPR183 to reduce inflammation)

What this could lead to

If successful, this could point toward a new daily pill to control lupus nephritis and protect kidney function.

What could go wrong

This is a very early (Phase 1/2) trial with only 36 people, so it is primarily checking safety. It may not show clear benefit, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lupus nephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fujian Medical University Union Hospital

    RECRUITING

    Fuzhou, Fujian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fujian Provincial Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hebei Petro China Central Hospital

    TERMINATED

    Langfang, Hebei, China

  • Jinhua Municipal Centeral Hospital Medical Group

    RECRUITING

    Jinhua, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nanjing DrumTower Hospital of Nanjing University Medical School

    RECRUITING

    Nanjing, Jiangsu, 210008, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nantong First People's Hospital

    RECRUITING

    Nantong, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Renmin Hospital of Wuhan University

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shandong Provincial Hospital

    RECRUITING

    Jinan, Shandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sun Yai-sen Memorial Hospital, Sun Yai-sen University

    RECRUITING

    Guangzhou, Guandong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Xuzhou Medical University

    RECRUITING

    Xuzhou, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital Of Anhui Medical University

    RECRUITING

    Hefei, Anhui, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • West China Hospital, Sichuan University

    NOT_YET_RECRUITING

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Wuhan Hospital of Traditional Chinese and Western Medicine

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Xinxiang Central Hospital

    RECRUITING

    Xinxiang, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact