Early trial tests re-engineered immune cells against tough blood cancers

NCT ID NCT04155710

Summary

This early-stage study tested a new cell therapy called IOV-2001 for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma that had returned or stopped responding to standard drugs. The main goals were to find a safe dose and see if the treatment could shrink the cancer. It involved a small group of 7 patients whose own immune cells were collected, modified, and infused back to fight the cancer.

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Contacts and locations

Locations

  • Allegheny Health

    Pittsburgh, Pennsylvania, 15224, United States

  • Baptist Cancer Center

    Memphis, Tennessee, 38120, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • University of Cincinnati Medical Center

    Cincinnati, Ohio, 45219, United States

  • University of Utah, Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

Conditions

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