Experimental cell therapy shows promise in Hard-to-Treat blood cancers

NCT ID NCT04155710

First seen Jan 05, 2026 · Last updated Apr 24, 2026 · Updated 22 times

Summary

This early-phase study tested a new cell therapy called IOV-2001 in 7 patients with chronic lymphocytic leukemia or small lymphocytic lymphoma that had stopped responding to standard treatments. The therapy uses a patient's own immune cells to fight the cancer. The main goals were to find the right dose and check for safety and tumor shrinkage.

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Contacts and locations

Locations

  • Allegheny Health

    Pittsburgh, Pennsylvania, 15224, United States

  • Baptist Cancer Center

    Memphis, Tennessee, 38120, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • University of Cincinnati Medical Center

    Cincinnati, Ohio, 45219, United States

  • University of Utah, Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.