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Which invisalign bump works best? new study aims to find out

NCT ID NCT07215598

Knowledge-focused Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at the small tooth-colored bumps (attachments) used with Invisalign aligners to help move teeth. Researchers want to see which design—optimized or conventional—is placed more accurately and holds its shape longer. Thirty adults starting Invisalign treatment will have their attachments scanned right after placement and at follow-up visits over six months to measure precision and wear.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Composite aligner attachments (optimized and conventional designs)
What this could lead to
If successful, this could help orthodontists choose better attachment designs for more predictable and efficient Invisalign treatment.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply to everyone. It focuses on accuracy and wear, not on treatment outcomes or side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged18 years or older. * Patients initiating Invisalign treatment with planned composite attachments. * Ability to provide written informed consent and agree to additional research intra-oral scans. * Good oral hygiene and absence of active periodontal disease at enrollment. Exclusion Criteria: * Extensive dental restorations (composites, crowns, veneers) on study teeth that could interfere with attachment bonding. * Enamel defects or severe wear on study tooth surfaces affecting bonding accuracy. * Contraindications to digital intraoral scanning (e.g., severe gag reflex, metallic prostheses preventing accurate imaging). * Severe tooth malposition that would compromise accurate attachment placement. * Poor oral hygiene or active periodontal disease at enrollment and/or if the patient develops poor oral hygiene or active periodontal disease during treatment.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clear aligner appliance Volume assessment Wear, restoration

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Maryland School of Dentistry

    Baltimore, Maryland, 21201, United States

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