New bladder treatment could spare kids with spina bifida from repeated surgeries

NCT ID NCT07027020

First seen Apr 22, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This study tests whether giving the drug oxybutynin directly into the bladder can help children with spina bifida who have bladder problems. The goal is to increase bladder capacity and reduce the need for more invasive treatments like Botox injections or surgery. About 60 children whose current oral medications are not working well or cause side effects will be randomly assigned to receive either the bladder-instilled drug or a placebo for 4 weeks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier De Colmar

    NOT_YET_RECRUITING

    Colmar, France

  • Centre Hospitalier Et Universitaire De Limoges

    NOT_YET_RECRUITING

    Limoges, France

  • Centre Hospitalier Régional De Marseille

    NOT_YET_RECRUITING

    Marseille, France

  • Centre Hospitalier Régional Et Universitaire De Brest

    NOT_YET_RECRUITING

    Brest, France

  • Centre Hospitalier Régional Et Universitaire de Nancy

    RECRUITING

    Vandœuvre-lès-Nancy, France

  • Centre Hospitalier Universitaire De Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, France

  • Centre Hospitalier Universitaire De Caen Normandie

    NOT_YET_RECRUITING

    Caen, France

  • Centre Hospitalier Universitaire De Saint Etienne

    NOT_YET_RECRUITING

    Saint-Etienne, France

  • Centre Hospitalier Universitaire Grenoble Alpes

    NOT_YET_RECRUITING

    Grenoble, France

  • Centre Hospitalier Universitaire de Besançon

    NOT_YET_RECRUITING

    Besançon, France

  • Centre Hospitalier Universitaire de Clermont-Ferrand

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

  • Centre Hospitalier Universitaire de Lille

    NOT_YET_RECRUITING

    Lille, France

  • Centre Hospitalier Universitaire de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

  • Centre Hospitalier Universitaire de Rennes

    NOT_YET_RECRUITING

    Rennes, France

  • Fondation Lenval Nice

    NOT_YET_RECRUITING

    Nice, France

  • Hôpital Necker Enfants Malades

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital Trousseau (chirurgie viscérale pédiatrique et néonatale)

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital Trousseau (médecine physique et de réadaptation pédiatrique)

    NOT_YET_RECRUITING

    Paris, France

  • Les Hopitaux Universitaires De Strasbourg

    NOT_YET_RECRUITING

    Strasbourg, France

Conditions

Explore the condition pages connected to this study.