New hope for mesothelioma patients who Can't have surgery?

NCT ID NCT05449366

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a chemotherapy drug called paclitaxel, given directly into the abdomen, for people with a rare cancer called malignant peritoneal mesothelioma. The 7 participants could not have standard surgery. The main goal was to find the safest dose and see if the treatment is feasible. Researchers also checked for side effects and how the drug behaves in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Paclitaxel (chemotherapy drug given directly into the abdomen)

What this could lead to

If successful, this could provide a new treatment option for patients with peritoneal mesothelioma who cannot have surgery, potentially controlling the disease and improving survival.

What could go wrong

This is a very small, early-phase study (only 7 participants) focused on finding the right dose and checking safety. It is not designed to prove the treatment works, and side effects from chemotherapy are expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant peritoneal mesothelioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Erasmus Medical Center

    Rotterdam, South Holland, 3000 CA, Netherlands