Could a nasal spray curb alcohol cravings?
NCT ID NCT05988632
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This early-stage trial tests whether a single dose of insulin given as a nasal spray can reduce alcohol cravings and consumption in people with alcohol use disorder. Forty non-treatment-seeking volunteers will receive either insulin or a placebo and then be exposed to alcohol-related cues and an alcoholic drink. The study primarily checks for safety and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intranasal insulin (Novolin R)
What this could lead to
If it works, this could point toward a new, non-addictive treatment option for alcohol use disorder that reduces cravings and drinking.
What could go wrong
This is a very early, small trial (40 people) testing only a single dose. It may not show any effect on drinking behavior, and the results may not apply to people seeking treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brown University
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••