Could a Skin-Deep shot beat the needle for dengue protection?

NCT ID NCT06837116

Completed ⭐️ VACCINE ⭐️ Sponsor: Prince of Songkla University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether giving the Qdenga dengue vaccine into the skin (intradermal) works as well as the standard shot under the skin. 29 healthy Thai adults who had never received a dengue vaccine took part. Researchers measured antibody and T-cell levels at day 0, 30, and 120 to compare immune responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Qdenga dengue vaccine
What this could lead to: If successful, this could show that a smaller, intradermal dose of the dengue vaccine is effective, potentially making vaccination faster and easier.
What could go wrong: This is a very early pilot study with only 29 people, so results may not apply to larger populations. The intradermal route might not trigger a strong enough immune response.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dengue disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENGUE

Contacts and locations

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Locations

Faculty of Medicine, Prince of Songkla University

Hat Yai, Changwat Songkhla, 90110, Thailand
Prince of Songkla university

Hat Yai, Changwat Songkhla, 90110, Thailand

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