Can a 16:8 fasting schedule beat standard dieting for weight loss?
NCT ID NCT07826065
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers compare two weight-loss strategies in 66 obese women: a 16:8 time-restricted eating plan (fasting 16 hours, eating within 8 hours) plus home exercise, versus a standard calorie-restricted diet plus home exercise. Over 12 weeks, they measure changes in body composition, blood sugar control, cholesterol levels, and liver enzymes. The trial asks whether the timing of eating matters as much as how much you eat.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 16:8 time-restricted feeding (intermittent fasting) combined with home-based exercise
- What this could lead to
- If the fasting approach works better than a standard diet, it could offer a simpler eating schedule for weight loss and metabolic health in women with obesity.
- What could go wrong
- This is a small, short study in a specific group, so results may not apply broadly. Weight loss approaches often fail long term, and fasting can be hard to stick with.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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66 people
The number who actually took part.
- Started
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May 2025
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Body Mass Index between 30 and 40 2. Female 3. Agreeing to adhere to a calorie-restricted diet 4. Agreeing to adhere to an exercise program Exclusion Criteria: 1. Having cancer, diabetes, or thyroid disease 2. Having received assistance with weight loss in the last 3 months 3. Inability to adhere to calorie restriction 4. Failure to adhere to an exercise program
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Erciyes University
Kayseri, Kayseri, 38100, Turkey (Türkiye)
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