Lung cancer radiation trial halted early – only 6 patients enrolled

NCT ID NCT02764086

Terminated Disease control Sponsor: Cancer Trials Ireland Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested whether giving a higher radiation dose directly to the lung tumor (while keeping standard doses to surrounding areas) is safe for people with non-small cell lung cancer. Only 6 participants were enrolled before the study was terminated. The goal was to find the highest safe dose without causing severe side effects, especially to the esophagus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (higher dose to tumor, standard dose to surrounding area)
What this could lead to: If successful, this approach could help doctors safely give higher radiation doses to lung tumors, potentially improving tumor control.
What could go wrong: This was a very early, small trial that was terminated early with only 6 participants. The higher radiation dose may cause more side effects, especially to the esophagus.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

St Lukes Radiation Oncology Network (SLRON) at St Luke's Hospital and St James Hospital

Dublin, Ireland

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