Liver hormone secrets revealed: new study could reshape diabetes drugs

NCT ID NCT07300982

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the hormone glucagon works with insulin in the liver to manage blood sugar. Researchers want to understand glucagon's multiple, sometimes opposite, roles to create better diabetes medicines. Forty healthy adults aged 18-45 will have two 5-hour sessions where they receive either glucagon or a saltwater solution while their blood sugar is kept steady. The goal is to learn how these hormones improve the liver's response to insulin.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke Center for Living

    Durham, North Carolina, 27705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••