DIABETES (DM)

This study tests whether trained female community health volunteers can effectively manage high blood pressure and diabetes in rural Nepal. About 400 adults with these conditions will receive health education, peer support, and monitoring from local volunteers, instead of relying…

This study tests whether regular visits with a dietitian-nutritionist can improve blood sugar control better than a hospital day program for people with type 2 diabetes. About 140 adults on insulin who have poor blood sugar control will take part. The main goal is to see which ap…

This study tests whether newer diabetes drugs (SGLT2 inhibitors and DPP-4 inhibitors) can delay the onset or worsening of diabetic retinopathy, an eye complication of diabetes. Researchers will compare these newer drugs to older ones like metformin in 70 adults with type 2 diabet…

This study tests whether adding reminders to electronic medical records helps doctors provide better care for people with pre-diabetes. About 6000 adults aged 21-59 will take part. Some clinics will use the reminders; others will not. The goal is to see if the prompts lead to mor…

This study tests whether a single dose of arginine, a natural amino acid, can help people with type 2 diabetes recover faster from diabetic ketoacidosis (DKA), a serious condition where blood sugar is very high and acids build up. The trial will enroll 60 adults in emergency room…

This study aims to identify subgroups of people with diabetes who share similar patterns between their blood sugar levels and mental health. Researchers will use smartphone surveys and continuous glucose monitors to collect data from over 1,800 participants over two years. The go…

This study is observing 200 adults with chronic kidney disease and a type of heart failure to see how a class of diabetes drugs called flozins affects their heart and kidney health over time. Researchers will measure things like heart attacks, strokes, hospitalizations, and kidne…

This study looks at heart plaque in people with diabetes using a special camera that combines two imaging methods. Researchers want to see if a new measurement can help predict serious heart problems like heart attacks or chest pain. About 1,500 participants will be followed for …

This study looks at how alpha cells in the pancreas talk to beta cells to control blood sugar. Researchers want to understand this communication better in people with and without diabetes. The study involves 30 adults and uses special tests to measure insulin and other signals. I…

This study looks at how heart rate and pumping strength are linked to metabolism in people with heart failure and diabetes. Researchers will take small samples of fat, muscle, and blood during pacemaker surgery to study these connections. The goal is to learn more about heart-mus…