Could a simple amino acid shorten diabetic emergencies?

NCT ID NCT07167693

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a single infusion of arginine hydrochloride, a natural amino acid, can help people with type 2 diabetes recover faster from diabetic ketoacidosis (DKA), a serious complication. Sixty adults arriving at emergency rooms with DKA will receive either arginine or a placebo alongside standard care. The goal is to see if arginine boosts the body's own insulin production, clearing ketones more quickly and reducing the need for additional insulin.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

arginine hydrochloride

What this could lead to

If it works, this could offer a simple, safe way to shorten hospital stays and reduce insulin needs during diabetic ketoacidosis in type 2 diabetes.

What could go wrong

This is an early phase 1/2 trial with only 60 participants, so results may not apply broadly. The infusion may cause temporary side effects like flushing or nausea, and benefits are not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus diabetes mellitus, ketosis-prone diabetic ketoacidosis hyperglycemia type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Detroit Medical Center

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••