Could a simple amino acid shorten diabetic emergencies?
NCT ID NCT07167693
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a single infusion of arginine hydrochloride, a natural amino acid, can help people with type 2 diabetes recover faster from diabetic ketoacidosis (DKA), a serious complication. Sixty adults arriving at emergency rooms with DKA will receive either arginine or a placebo alongside standard care. The goal is to see if arginine boosts the body's own insulin production, clearing ketones more quickly and reducing the need for additional insulin.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- arginine hydrochloride
- What this could lead to
- If it works, this could offer a simple, safe way to shorten hospital stays and reduce insulin needs during diabetic ketoacidosis in type 2 diabetes.
- What could go wrong
- This is an early phase 1/2 trial with only 60 participants, so results may not apply broadly. The infusion may cause temporary side effects like flushing or nausea, and benefits are not guaranteed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Detroit Medical Center
RECRUITINGDetroit, Michigan, 48201, United States
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