Flozins under the microscope: can they protect heart and kidneys in High-Risk patients?

NCT ID NCT07237451

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study follows 200 adults with chronic kidney disease and a type of heart failure (HFpEF), some taking SGLT2 inhibitors (flozins) and some not. Researchers will measure arterial stiffness, heart function, and kidney decline over time to see if flozins are linked to better outcomes. The goal is to gather real-world evidence, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SGLT2 inhibitors (flozins)

What this could lead to

If successful, this study could clarify how SGLT2 inhibitors affect heart and kidney health in patients with chronic kidney disease and heart failure.

What could go wrong

This is an observational study, not a controlled trial, so it can show links but not prove cause and effect. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome diabetes mellitus diastolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dr. C.I. Parhon Hospital in Iasi

    RECRUITING

    Iași, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact