Flozins under the microscope: can they protect heart and kidneys in High-Risk patients?

NCT ID NCT07237451

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study follows 200 adults with chronic kidney disease and a type of heart failure (HFpEF), some taking SGLT2 inhibitors (flozins) and some not. Researchers will measure arterial stiffness, heart function, and kidney decline over time to see if flozins are linked to better outcomes. The goal is to gather real-world evidence, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SGLT2 inhibitors (flozins)
What this could lead to
If successful, this study could clarify how SGLT2 inhibitors affect heart and kidney health in patients with chronic kidney disease and heart failure.
What could go wrong
This is an observational study, not a controlled trial, so it can show links but not prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dr. C.I. Parhon Hospital in Iasi

    RECRUITING

    Iași, Romania

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