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Synthetic membrane could help grow jawbone for dental implants

NCT ID NCT07701473

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether a new synthetic membrane, called Inox Nanoksa G-Plus, can help rebuild bone in the upper or lower jaw for adults who need dental implants but lack sufficient bone width or height. All participants receive the same surgery: the membrane is placed under the gums along with a bone graft material to guide new bone growth. The study measures pain, swelling, and bleeding in the first week, and uses 3D X-rays at 6 months to check how much new bone formed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Inox Nanoksa G-Plus Membrane, a synthetic non-resorbable barrier used with bone graft to rebuild jawbone
What this could lead to
If successful, this membrane could offer a reliable synthetic option for jawbone rebuilding, helping more people get dental implants without needing a second surgical site for bone harvesting.
What could go wrong
This is a very small early study (12 people) with no comparison group, so results may not apply broadly. Risks include infection, membrane exposure, or insufficient bone growth.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 12 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Partial edentulism in the maxilla or mandible requiring single or multiple implant-supported restorations. * Insufficient bone volume for standard implant placement, defined as: * Horizontal defect: residual ridge width \< 5 mm at the intended implant site, OR * Vertical defect: residual ridge height \< 8 mm above vital structures (mandibular canal, maxillary sinus, nasal floor). * Healthy oral mucosa with no signs of active infection or inflammation at the defect site. * Systemically healthy or with well-controlled medical conditions (American Society of Anesthesiologists - ASA class I or II). Exclusion Criteria: * Untreated periodontitis or active peri-implant disease. * Current or previous treatment with intravenous bisphosphonates (or oral bisphosphonates for \> 3 years). * Severe immunosuppression or chronic systemic corticosteroid therapy (\> 10 mg/day prednisolone for \> 3 months). * Active smoking (\> 10 cigarettes per day). Smoking cessation for at least 2 weeks before surgery is required; heavy smokers may be excluded. * Pregnant or lactating women.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone loss Alveolar ridge deficiency

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Department of Periodontics, Faculty of Dentistry, Cairo University

    Cairo, Cairo Governorate, 11553, Egypt

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