Glow-in-the-Dark dye could replace radioactive tracer in breast cancer surgery

NCT ID NCT07441733

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether a fluorescent dye called indocyanine green (ICG) can effectively identify sentinel lymph nodes in breast cancer patients, potentially replacing the standard radioactive tracer. Forty women with early-stage breast cancer will receive both methods, and doctors will compare how often each finds the nodes. If ICG works as well, it could simplify the procedure and avoid radioactivity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Indocyanine Green (ICG)

What this could lead to

If successful, this could replace the standard radioactive tracer with a safer, more accessible dye for sentinel lymph node biopsy in breast cancer.

What could go wrong

This is a small pilot study (40 participants) at a single hospital, so results may not apply broadly. ICG may not identify nodes as reliably as the current method.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ospedale P. Pederzoli Casa di Cura Privata S.p.A.

    RECRUITING

    Peschiera del Garda, Verona, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••