New hope for skin cancer patients suffering from severe gut side effects of immunotherapy

NCT ID NCT04305145

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This study tests if the drug infliximab can treat severe colitis (gut inflammation) caused by immunotherapy in people with advanced skin cancer. About 42 participants will receive either infliximab or steroids to see which works better at stopping symptoms without needing long-term steroids. The goal is to find a safer, more effective way to manage this common side effect.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.