Can a drug for arthritis beat steroids for immunotherapy side effects?

NCT ID NCT04305145

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 28 times

Summary

This study compares infliximab, a drug used for arthritis, to standard steroids for treating colitis (inflammation of the colon) caused by immunotherapy in people with advanced skin cancer. About 42 participants will receive either infliximab or steroids to see which leads to faster recovery without needing ongoing steroids. The goal is to find a better way to manage this common side effect so patients can continue their cancer treatment.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.