Liver function may change how inavolisib works
NCT ID NCT07144111
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-phase study looks at how a single dose of the drug inavolisib behaves in people with moderate or severe liver impairment compared to healthy volunteers. Researchers will measure drug levels in the blood and check for side effects. The goal is to understand if liver problems change how the drug is processed, which could guide future dosing recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
inavolisib
What this could lead to
If successful, this study could help doctors understand how to dose inavolisib safely for patients with liver problems.
What could go wrong
This is a very early, small study (32 people) focused on drug levels, not on treating a disease. Results may not apply to real-world use.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Orange County Research Center
RECRUITINGLake Forest, California, 92630, United States
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Orlando Clinical Research Center
RECRUITINGOrlando, Florida, 32809, United States
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Pinnacle Clinical Research - San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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The Texas Liver Institute, Inc.
RECRUITINGSan Antonio, Texas, 78215, United States