New combo aims to shrink tumors in hard-to-treat breast cancer

NCT ID NCT07368998

First seen Feb 01, 2026 · Last updated May 14, 2026 · Updated 20 times

Summary

This study tests two different doses of inavolisib (a targeted drug) plus fulvestrant (hormone therapy) in 80 people with a specific type of advanced breast cancer (PIK3CA-mutated, HR+, HER2-). The goal is to see if a lower dose works as well with fewer side effects. Participants must have already tried a CDK4/6 inhibitor and hormone therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Adana Baskent University Hospital

    RECRUITING

    Adana, 01120, Turkey (Türkiye)

  • Astera Cancer Care East Brunswick

    RECRUITING

    East Brunswick, New Jersey, 08816, United States

  • Bagcilar Medipol Mega Universitesi Hastanesi

    RECRUITING

    Bağcılar, Istanbul, 34214, Turkey (Türkiye)

  • Bendigo Cancer Centre

    RECRUITING

    Bendigo, Victoria, 3550, Australia

  • Blackpool Victoria Hospital

    RECRUITING

    Blackpool, FY3 8NR, United Kingdom

  • Centro Oncologico Korben

    RECRUITING

    Ciudad Autonoma Buenos Aires, C1426AGE, Argentina

  • Cliniques Universitaires St-Luc

    RECRUITING

    Brussels, 1200, Belgium

  • Hospital Clinico Universitario de Valencia

    RECRUITING

    Valencia, 46010, Spain

  • Hospital Provincial del Centenario

    RECRUITING

    Rosario, S2002KDS, Argentina

  • Hospital Universitari Vall d'Hebron;Oncology

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario 12 De Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario San Cecilio

    RECRUITING

    Granada, 18016, Spain

  • Jessa Zkh (Campus Virga Jesse)

    RECRUITING

    Hasselt, 3500, Belgium

  • Los Angeles Cancer Network

    RECRUITING

    Los Angeles, California, 90017-4803, United States

  • Medical Park Seyhan Hospital

    RECRUITING

    Seyhan, Turkey (Türkiye)

  • Memorial Ankara Hastanesi

    RECRUITING

    Ankara, 06520, Turkey (Türkiye)

  • Mount Vernon Cancer Centre

    RECRUITING

    Northwood, Middlesex, HA6 2RN, United Kingdom

  • Princess Alexandra Hospital

    RECRUITING

    Harlow, CM20 1QX, United Kingdom

  • UZ Leuven Gasthuisberg

    RECRUITING

    Leuven, 3000, Belgium

Conditions

Explore the condition pages connected to this study.