New shot could help when arthritis drugs fail

NCT ID NCT06754462

Ongoing Disease control Sponsor: Immunovant Sciences GmbH Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called IMVT-1402 in 120 adults with active, difficult-to-treat rheumatoid arthritis. Participants receive weekly injections of either the drug or a placebo. The goal is to see if the drug helps maintain symptom improvement over 28 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: IMVT-1402 (a drug given as a weekly injection under the skin)
What this could lead to: If it works, this could provide a new treatment option for people with hard-to-treat rheumatoid arthritis, helping them maintain symptom control.
What could go wrong: This is a mid-stage trial with only 120 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune disease rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

Locations

Site Number - 1000

Duncansville, Pennsylvania, 16635, United States
Site Number - 1001

Gainesville, Georgia, 30501, United States
Site Number - 1002

Miami, Florida, 33143, United States
Site Number - 1004

Charlotte, North Carolina, 28207, United States
Site Number - 1005

Winter Park, Florida, 32789, United States
Site Number - 1006

Cumberland, Maryland, 21502, United States
Site Number - 1007

Hagerstown, Maryland, 21740, United States
Site Number - 1008

Worcester, Massachusetts, 01605, United States
Site Number - 1010

Summit, New Jersey, 07901, United States
Site Number - 1012

Zephyrhills, Florida, 33542, United States
Site Number - 1013

Tomball, Texas, 77375, United States
Site Number - 1014

Mesquite, Texas, 75150, United States
Site Number - 1015

Jupiter, Florida, 33458, United States
Site Number - 1016

Jackson, Tennessee, 38305, United States
Site Number - 1017

Colleyville, Texas, 76034, United States
Site Number - 1018

Mesa, Arizona, 85210, United States
Site Number - 1019

Sun City, Arizona, 85351, United States
Site Number - 1020

Denver, Colorado, 80230, United States
Site Number - 1021

Saint Clair Shores, Michigan, 48081, United States
Site Number - 1022

Covina, California, 91722, United States
Site Number - 1023

Whittier, California, 90602, United States
Site Number - 1024

Temecula, California, 92592, United States
Site Number - 1025

Tomball, Texas, 77377, United States
Site Number - 1026

Memphis, Tennessee, 38119, United States
Site Number - 1027

Plantation, Florida, 33324, United States
Site Number - 1028

San Leandro, California, 94578, United States
Site Number - 1029

Murfreesboro, Tennessee, 37128, United States
Site Number - 1030

Kansas City, Missouri, 64151, United States
Site Number - 1031

Rockville, Maryland, 20850, United States
Site Number - 1033

Tujunga, California, 91042, United States
Site Number - 1034

Chicago, Illinois, 60607, United States
Site Number - 1035

Statesville, North Carolina, 28625, United States
Site Number - 1036

Katy, Texas, 77494, United States
Site Number - 1037

Allen, Texas, 75013, United States
Site Number - 3000

Poznan, 61-397, Poland
Site Number - 3002

Wroclaw, 53-673, Poland
Site Number - 3003

Sochaczew, 96-500, Poland
Site Number - 3004

Warsaw, 02-665, Poland
Site Number - 3005

Bialystok, 15-879, Poland
Site Number - 3006

Nadarzyn, 05-830, Poland
Site Number - 3007

Elblag, 82-300, Poland
Site Number - 3008

Poznan, 60-848, Poland
Site Number - 3009

Lublin, 20-607, Poland
Site Number - 3200

Zlín, 760 01, Czechia
Site Number - 3201

Uherské Hradiště, 686 01, Czechia
Site Number - 3202

Ostrava, 702 00, Czechia
Site Number - 3203

Praha 2 Nove Mesto, 128 50, Czechia
Site Number - 3204

Brno, 638 00, Czechia
Site Number - 5000

San Miguel de Tucumán, 4000, Argentina
Site Number - 5001

Buenos Aires, 1425, Argentina
Site Number - 5002

Buenos Aires, C1118AAF, Argentina
Site Number - 5003

Buenos Aires, 1417, Argentina
Site Number - 5005

Buenos Aires, C1180AAX, Argentina
Site Number - 5600

Sofia, 1336, Bulgaria
Site Number - 5601

Sofia, 1680, Bulgaria
Site Number - 5602

Plovdiv, 4004, Bulgaria
Site Number - 5603

Plovdiv, 4000, Bulgaria
Site Number - 5604

Rousse, 7000, Bulgaria
Site Number - 5605

Plovdiv, 4002, Bulgaria
Site Number - 5606

Sevlievo, 5400, Bulgaria
Site Number - 6500

Hamburg, 20095, Germany
Site Number - 6501

Ratingen, 40878, Germany
Site Number - 7000

Edinburgh, EH4 2XU, United Kingdom
Site Number - 7001

London, SE5 9RJ, United Kingdom
Site Number - 7003

Wolverhampton, WV10 0QP, United Kingdom
Site Number - 7100

Seville, 41009, Spain
Site Number - 7101

Bilbao, 48013, Spain
Site Number - 7102

Málaga, 29009, Spain
Site Number - 7104

Barcelona, 08208, Spain
Site Number - 7500

Brasov, 500283, Romania
Site Number - 7501

Râmnicu Vâlcea, 240636, Romania
Site Number - 7502

Bucharest, 020475, Romania
Site Number - 7550

Hódmezővásárhely, 6800, Hungary
Site Number - 7551

Székesfehérvár, 8000, Hungary
Site Number - 7552

Veszprém, 8200, Hungary
Site Number - 7553

Kecskemét, 6000, Hungary
Site Number - 7554

Budapest, 1027, Hungary
Site Number - 7555

Budapest, 1027, Hungary
Site Number - 8000

Tbilisi, 0159, Georgia
Site Number - 8001

Tbilisi, 0160, Georgia
Site Number - 8003

Tbilisi, 0186, Georgia
Site Number -5004

Buenos Aires, C1046, Argentina
Site Number -7002

North Shields, NE29 8NH, United Kingdom

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